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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Alzheimer Dis Assoc Disord. 2013 Jul-Sep;27(3):226–232. doi: 10.1097/WAD.0b013e31826f040d

Table 2.

The prevalence of individual extrapyramidal signs in each diagnostic group, and odds ratios for a Lewy body diagnosis (DLB+LBV) from univariate models (adjusted for age, education, gender and MMSE).

Within Group Prevalence (%)* Unadjusted OR of LB diagnosis* [95% CI] Adjusted OR of LB diagnosis* [95% CI]
AD DLB LBV
Masked Facies 4.2 48.5 24.8 14.0 [9.9–19.9] 18.6 [12.2–28.3]
Speech/Hypophonia 3.4 30.8 11.4 8.1 [5.4–12.0] 14.1 [8.4–23.4]
Rigidity 9.8 44.6 37.1 6.5 [4.8–8.7] 7.0 [5.1–9.8]
Impaired Posture/Gait 14.2 43.1 31.4 3.7 [2.7–4.9] 6.4 [4.4–9.1]
Bradykinesia 19.3 55.4 46.7 4.4 [3.3–5.8] 5.9 [4.3–8.1]
Impaired Chair Rise 15.4 28.9 28.7 2.2 [1.6–3.0] 4.5 [3.1–6.5]
Resting Tremor 3.2 13.9 7.6 3.7 [2.3–6.0] 3.9 [2.4–6.6]
Postural Instability 12.5 26.2 20.6 2.2 [1.6–3.1] 3.8 [2.6–5.6]
Action/Postural Tremor 6.2 12.3 18.1 2.6 [1.7–3.9] 2.5 [1.6–3.8]

Using a cutoff of ≥1 for Resting Tremor resulted in an adjusted odds ratio of 3.0 [2.1–4.2], with a prevalence of 11.9% in AD subjects, 30.8% in DLB and 23.8% in LBV. Using ≥2 for posture and ≥1 for the gait component in Impaired Posture/Gait, yielded an OR of 7.7 [5.4–11.0] with prevalences of 42.1% in AD, 82.3% in DLB, and 71.4% in LBV

*

All p-values <0.0001