Table 2.
Within Group Prevalence (%)* | Unadjusted OR of LB diagnosis* [95% CI] | Adjusted OR of LB diagnosis* [95% CI] | ||||
---|---|---|---|---|---|---|
AD | DLB | LBV | ||||
Masked Facies | 4.2 | 48.5 | 24.8 | 14.0 [9.9–19.9] | 18.6 [12.2–28.3] | |
Speech/Hypophonia | 3.4 | 30.8 | 11.4 | 8.1 [5.4–12.0] | 14.1 [8.4–23.4] | |
Rigidity | 9.8 | 44.6 | 37.1 | 6.5 [4.8–8.7] | 7.0 [5.1–9.8] | |
Impaired Posture/Gait | 14.2 | 43.1 | 31.4 | 3.7 [2.7–4.9] | 6.4 [4.4–9.1] | |
Bradykinesia | 19.3 | 55.4 | 46.7 | 4.4 [3.3–5.8] | 5.9 [4.3–8.1] | |
Impaired Chair Rise | 15.4 | 28.9 | 28.7 | 2.2 [1.6–3.0] | 4.5 [3.1–6.5] | |
Resting Tremor | 3.2 | 13.9 | 7.6 | 3.7 [2.3–6.0] | 3.9 [2.4–6.6] | |
Postural Instability | 12.5 | 26.2 | 20.6 | 2.2 [1.6–3.1] | 3.8 [2.6–5.6] | |
Action/Postural Tremor | 6.2 | 12.3 | 18.1 | 2.6 [1.7–3.9] | 2.5 [1.6–3.8] |
Using a cutoff of ≥1 for Resting Tremor resulted in an adjusted odds ratio of 3.0 [2.1–4.2], with a prevalence of 11.9% in AD subjects, 30.8% in DLB and 23.8% in LBV. Using ≥2 for posture and ≥1 for the gait component in Impaired Posture/Gait, yielded an OR of 7.7 [5.4–11.0] with prevalences of 42.1% in AD, 82.3% in DLB, and 71.4% in LBV
All p-values <0.0001