Table 3.
Dilution of lysate samples derived from culture supernatants at which the assays positively detect (s/co ≥1.0) specific HIV subtype antigen or antibody
| HIV subtype | Elecsys® HIV combi PT | ADVIA centaur® HIV Ag/Ab combo | AxSYM® HIV Ag/Ab combo | ARCHITECT® HIV Ag/Ab combo |
|---|---|---|---|---|
| HIV antigen | ||||
| A | 1:64,000 | 1:64,000 | 1:64,000 | 1:128,000 |
| B | 1:37,280 | 1:18,640 | 1:37,280 | 1:37,280 |
| C | 1:26,720 | 1:26,720 | 1:26,720 | 1:53,440 |
| D | 1:21,280 | 1:21,280 | 1:21,280 | 1:42,560 |
| E | 1:31,968 | 1:7,992 | 1:31,968 | 1:63,936 |
| F | 1:15,936 | 1:15,936 | 1:7,968 | 1:15,936 |
| G | 1:52,896 | 1:26,448 | 1:52,896 | 1:105,792 |
| H | 1:11,376 | 1:11,376 | 1:11,376 | 1:22,752 |
| O | 1:256 | Failed to detect diluted antigen | 1:128 | 1:512 |
| HIV-2 | 1:64 | Failed to detect diluted antigen | 1:8 | Failed to detect diluted antigen |
| HIV antibodya | ||||
| A | 1:170,000 | 1:17,000 | 1:17,000 | 1:17,000 |
| A | 1:5,000 | 1:5,000 | 1:5,000 | 1:500 |
| B | 1:15,000 | 1:1,500 | 1:1,500 | 1:1,500 |
| B | 1:120,000 | 1:120,000 | 1:120,000 | 1:120,000 |
| C | 1:100,000 | 1:10,000 | 1:100,000 | 1:10,000 |
| C | 1:200,000 | 1:200,000 | 1:200,000 | 1:200,000 |
| D | 1:50,000 | 1:5,000 | 1:5,000 | 1:5,000 |
| D | 1:28,500 | 1:28,500 | 1:28,500 | 1:2,850 |
| E | 1:50,000 | 1:500 | 1:5,000 | 1:500 |
| E | 1:50,000 | 1:5,000 | 1:5,000 | 1:500 |
| F | 1:22,800 | 1:228 | 1:2,280 | 1:2,280 |
| F | 1:100,000 | 1:100,000 | 1:100,000 | 1:100,000 |
| G | 1:35,000 | 1:35,000 | 1:35,000 | 1:3,500 |
| G | 1:140,000 | 1:140,000 | 1:14,000 | 1:14,000 |
| O | 1:10,000 | Failed to detect diluted antibody | 1:10,000 | 1:1,000 |
| O | 1:500,000 | Failed to detect diluted antibody | 1:5,000 | 1:5,000 |
| HIV-2 | 1:50,000 | 1:500 | 1:5,000 | 1:500 |
| HIV-2 | 1:60,000 | 1:600 | 1:6,000 | 1:6,000 |
aTwo different antibody samples were tested for each subtype