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. Author manuscript; available in PMC: 2014 Jan 28.
Published in final edited form as: Dev Cell. 2013 Jan 28;24(2):159–168. doi: 10.1016/j.devcel.2012.12.005

Figure 3. Tango1 mediates Col IV ER exit predominantly at basal tER sites.

Figure 3

(A) Tango1 is strongly enriched at basal tER-Golgi units, as indicated by the cis-Golgi marker, GM130. Dashed lines mark the apical surface. (B) An optical section through the basal cytoplasm showing co-localization between Tango1, GM130 and Vkg-GFP. (C) Tango1-RNAi causes Vkg-GFP to accumulate in the basal ER. Experiments performed at stages 7–8. Scale bars are 10 μm. See also Figure S3.

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