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. 2012 Jul 11;32(1):11–24. doi: 10.1002/sim.5524

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Copyright © 2012 John Wiley & Sons, Ltd.

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Contours for conditional power of 90% for an updated meta-analysis to detect a standardized mean difference of − 0.5, having observed a standardized mean difference of − 0.58 (95% CI − 1.43 to 0.27), based on a meta-analysis of allergic rhinitis symptom scores after sublingual immunotherapy for allergic rhinitis caused by house dust mites ¹⁹. The graph illustrates the relationship between additional information size (expressed as sample size) and number of planned studies for three values of future heterogeneity, .

Inline graphic — Contours for conditional power of 90% for an updated meta-analysis to detect a standardized mean difference of − 0.5, having observed a standardized mean difference of − 0.58 (95% CI − 1.43 to 0.27), based on a meta-analysis of allergic rhinitis symptom scores after sublingual immunotherapy for allergic rhinitis caused by house dust mites ¹⁹. The graph illustrates the relationship between additional information size (expressed as sample size) and number of planned studies for three values of future heterogeneity, .