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Combination of the AM with 5-FU or cisplatin increases the TGI in the Colon 26 colon carcinoma model. (a) Mice were treated with 5-FU, with AM, or with 5-FU and AM. *p < 0.05, **p < 0.001 vs. control; #p < 0.001 vs. 5-FU (ANOVA). B, Mice were treated with cisplatin, with AM, or with cisplatin and AM. *p < 0.05, **p < 0.001 vs. control; #p < 0.001 vs. cisplatin and vs. AM (ANOVA). Arrows indicate the last days of treatment. Error bars represent SEM.
