Table 2.
Comparison of hematological parameters and thyroid hormone levels in untreated and treated subclinical hypothyroid and primary hypothyroid patients.
| Parameters | Euthyroid N=180 | Subclinical hypothyroid | Primary hypothyroid | p-value | |||
|---|---|---|---|---|---|---|---|
| Untreated SCH n=110 Mean±SD | Treated SCH n=110 Mean±SD | Untreated Pr. Hypothyroid n= 100 Mean±SD | Treated Pr. Hypothyroid n=100 Mean±SD | Untreated primary hypothyroid vs. treated pr. hypothyroid | Untreated SCH vs. treated SCH | ||
| T3(ng/dl) | 1.052±0.17 | 1.062±0.28(0.0) | 1.060±0.28 (0.01) | 0.82±0.41(-0.01) | 0.82±0.41(-0.00) | 0.92 | 0.99 |
| T4(µg/dl) | 7.42±1.63(0.0) | 7.52±1.53(0.0) | 7.52±1.53(0.0) | 5.54±1.53(+2.06) | 9.54±2.53(-1.84) | <0.0001 | <0.0001 |
| TSH(µIU/ml) | 2.23±0. 93 | 19.37±10.54(-12.73) | 14.22±8.20(-3.67) | 18.67±11.34(-10.82) | 15.28±7.30(-5.46) | <0.001 | <0.001 |
| Hb(g/dl) | 14.72±1.77 | 10.83±1.33 | 12.01±1.20 | 10.73±0.86 | 12.64±1.33 | <0.001 | <0.001 |
| RBC(106/µl) | 5.15±1.59 | 4.21±0.66 | 5.14±0.62 | 4.63±0.51 | 5.14±0.62 | 0.04 | 0.01 |
| WBC(103/µl) | 7.4±1.06 | 6.71±0.91 | 6.81±1.01 | 7.25±0.86 | 6.14±0.96 | 0.006 | 0.002 |
| HCT(%) | 41.5±2 | 38.5±2.2 | 39.4±2.8 | 38.6±2.6 | 39.5±2.5 | <0.001 | <0.001 |
| MCV(fL) | 86.34±5.71 | 84.56±6.84 | 86.19±6.43 | 83.34±6.92 | 85.81±6.22 | <0.05 | <0.05 |
| LYM (%) | 34.63±7.85 | 31.44±12.55 | 19.82±11.4 | 17.85±9.19 | 28.17±13.6 | 0.008 | 0.006 |
| RBC (%) | 82.71±12.3 | 84.36±13.2 | 82.85±12.4 | 92.63±10.30 | 82.71±12.30 | 0.05 | 0.04 |
| RDW (fL) | - | 15.5±1.85 | 17.91±2.37 | 14.93±5.47 | 14.61±3.61 | 0.089 | 0.057 |