Figure 2.

Sputum IL-17A mRNA levels in CF patients without and with ABPA. Sputum mRNA was extracted from adult CF patients without (n = 22) and with (n = 9) ABPA and IL-17A mRNA levels were measured by real-time RT-PCR [44]. ABPA was defined on the basis of (1) deteriorating lung function, (2) immediate Aspergillus fumigatus (af) skin test reactivity, (3) serum total IgE > 1000 IU/mL, (4) elevated af specific IgE and IgG antibodies, and (5) chest radiographic infiltrates. *P < 0.05 by Mann-Withney U test.