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CIGB-552 modifies the redox status in lung cancer cells. H460 cells were treated with CIGB-552 (25 μM) for the indicated times. (a) Activity of SOD1, H460 siRNA was used as a control of the experiment. (b) Total antioxidant capacity measured by FRAP. (c) Levels of proteins and lipids peroxidation measured by concentration of malondialdeyde (MDA) and advanced oxidative protein products (AOPP). Means ± SD (n = 6). *P < 0.05 statistically significant. NT indicates untreated cells.
