Figure 1. Determination of optimal Mixl1 binding sequence by PCR-assisted binding site selection.

(A) Schematic diagram of the experimental procedure. (B) 32 sequenced oligonucleotides were aligned to the 11 bp TAATT-containing motif (underlined). A consensus sequence was compiled and converted to a sequence logo in which the height of letters represents the relative frequency of each nucleotide at each of the 11 positions ³⁹.