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. 2013 Feb;182(2):375–387. doi: 10.1016/j.ajpath.2012.10.014

Figure 6.

Figure 6

Effect of siRNA silencing of TLR-2 or TLR-5 on LPS-induced alteration in Caco-2 TER and inulin flux. Caco-2 cells were transfected with TLR-2 siRNA or TLR-5 siRNA for 24 hours before the LPS treatment. siRNA-induced silencing of TLR-2 did not affect Caco-2 TER (A) or inulin flux (B). The mean TER for control Caco-2 monolayers was 468 ± 17 Ω • cm2. siRNA-induced silencing of TLR-5 also did not affect Caco-2 TER (C) or inulin flux (D). The mean TER for control Caco-2 monolayers was 492 ± 24 Ω • cm2. Scr, scrambled. *P < 0.001 versus control.