Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Both p44/p42 and p38 MAPK are involved in LPS-induced cytokine/chemokine production in alveolar macrophages. A–C: MH-S cells were treated with 100 ng/mL LPS in the presence or absence of p44/42 MAPK inhibitor, U0126 (10 μmol/L), p38 MAPK inhibitor VII (10 μmol/L), or both for 8 hours. Supernatants were subjected to ELISA analysis for TNF-α (A), IL-6 (B), and MIP-2 (C) production. Data are presented as means ± SEM (n = 4 to 6). DMSO, dimethyl sulfoxide.
