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Structural switch from native state (Left) to A-state (Right). Corresponding structural elements are coded by identical colors: N-terminal β-hairpin (orange), central α-helix (magenta), and C-terminal half (green). The C-terminal half switches from a β-sheet structure in the native state to the long α-helix α′ in the A-state. The structural scheme of the A-state is adapted from Brutscher et al. (19).
