Table 2.

In vivo data for pgDIO and pgDR rats

	pgDR chow	pgDR HE	pgDIO chow	pgDIO HE	Interaction	Genotype	Diet
Average daily body weight gain (g)	4.7 ± 0.14***	5.3 ± 0.14###	6.8 ± 0.16	7.5 ± 0.32	P = 0.90	P < 0.0001	P = 0.004
Body weight at termination (g)	382.3 ± 10.1***	420.3 ± 9.7###	510.1 ± 11.4	552.4 ± 19.7	P = 0.87	P < 0.0001	P = 0.005
Average daily food intake (kcal)	86.1 ± 2.3***	92.8 ± 2.7##	109.0 ± 2.9	107.7 ± 4.1	P = 0.20	P < 0.0001	P = 0.37
Fat pad weight/body weight (%)	3.95 ± 0.3*	4.8 ± 0.6###	6.6 ± 0.7§§§	10.5 ± 0.8	P = 0.02	P < 0.0001	P = 0.0009

Data tested with two-way ANOVA with Bonferroni-corrected post-tests, n = 8 per group.

HE, high energy; pgDIO, polygenic diet-induced obese; pgDR, polygenic diet-resistant.

^*P < 0.05.

^***P < 0.001 between pgDR chow and pgDIO chow.

^##P < 0.01.

^###P < 0.001 between pgDR HE and pgDIO HE.

^§§§P < 0.001 between pgDIO chow and pgDIO HE.