Table 2.
pgDR chow | pgDR HE | pgDIO chow | pgDIO HE | Interaction | Genotype | Diet | |
---|---|---|---|---|---|---|---|
Average daily body weight gain (g) | 4.7 ± 0.14*** | 5.3 ± 0.14### | 6.8 ± 0.16 | 7.5 ± 0.32 | P = 0.90 | P < 0.0001 | P = 0.004 |
Body weight at termination (g) | 382.3 ± 10.1*** | 420.3 ± 9.7### | 510.1 ± 11.4 | 552.4 ± 19.7 | P = 0.87 | P < 0.0001 | P = 0.005 |
Average daily food intake (kcal) | 86.1 ± 2.3*** | 92.8 ± 2.7## | 109.0 ± 2.9 | 107.7 ± 4.1 | P = 0.20 | P < 0.0001 | P = 0.37 |
Fat pad weight/body weight (%) | 3.95 ± 0.3* | 4.8 ± 0.6### | 6.6 ± 0.7§§§ | 10.5 ± 0.8 | P = 0.02 | P < 0.0001 | P = 0.0009 |
Data tested with two-way ANOVA with Bonferroni-corrected post-tests, n = 8 per group.
HE, high energy; pgDIO, polygenic diet-induced obese; pgDR, polygenic diet-resistant.
P < 0.05.
P < 0.001 between pgDR chow and pgDIO chow.
P < 0.01.
P < 0.001 between pgDR HE and pgDIO HE.
P < 0.001 between pgDIO chow and pgDIO HE.