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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Metallomics. 2012 Jun 19;4(8):784–793. doi: 10.1039/c2mt20074k

Table 3.

Select GO Terms Associated with Up-Regulated Genes

Category Term # Genes p-value
 Arsenic
GOTERM_MF_FAT GO:0051059~NF-kappaB binding 6 1.8E-03
GOTERM_BP_FAT GO:0048661~positive regulation of smooth muscle cell proliferation 5 1.4E-02
GOTERM_MF_FAT GO:0004886~retinoid-X receptor activity 3 3.0E-02
GOTERM_MF_FAT GO:0003712~transcription cofactor activity 19 3.2E-02
GOTERM_BP_FAT GO:0006325~chromatin organization 19 3.3E-02
GOTERM_MF_FAT GO:0003713~transcription coactivator activity 13 3.4E-02
GOTERM_BP_FAT GO:0016568~chromatin modification 15 3.9E-02
GOTERM_BP_FAT GO:0046328~regulation of JNK cascade 6 4.7E-02
 Chromium
GOTERM_BP_FAT GO:0006928~cell motion 22 2.2E-03
GOTERM_CC_FAT GO:0030057~desmosome 4 9.0E-03
SP_PIR_KEYWORDS keratin 8 2.0E-02
GOTERM_BP_FAT GO:0007411~axon guidance 7 3.3E-02
GOTERM_BP_FAT GO:0048870~cell motility 13 4.2E-02
GOTERM_BP_FAT GO:0016477~cell migration 12 4.5E-02
 Nickel
GOTERM_BP_FAT GO:0048568~embryonic organ development 10 5.4E-03
GOTERM_BP_FAT GO:0001525~angiogenesis 9 7.2E-03
GOTERM_BP_FAT GO:0046328~regulation of JNK cascade 6 7.9E-03
GOTERM_BP_FAT GO:0040017~positive regulation of locomotion 7 1.1E-02
GOTERM_BP_FAT GO:0001666~response to hypoxia 8 1.5E-02
GOTERM_BP_FAT GO:0043408~regulation of MAPKKK cascade 7 1.8E-02
GOTERM_BP_FAT GO:0030335~positive regulation of cell migration 6 2.8E-02
GOTERM_BP_FAT GO:0051092~positive regulation of NF-kappaB TF activity 4 4.3E-02
 Vanadium
GOTERM_BP_FAT GO:0007155~celladhesion 26 3.0E-04
GOTERM_BP_FAT GO:0030521~androgen receptor signaling pathway 5 3.0E-03
GOTERM_BP_FAT GO:0045597~positive regulation of cell differentiation 11 5.4E-03
GOTERM_CC_FAT GO:0031012~extracellular matrix 13 9.8E-03
GOTERM_BP_FAT GO:0006928~cell motion 16 1.4E-02
GOTERM_BP_FAT GO:0016477~cell migration 11 1.8E-02
GOTERM_BP_FAT GO:0008361~regulation of cell size 9 2.3E-02
GOTERM_CC_FAT GO:0005925~focal adhesion 6 2.4E-02
GOTERM_CC_FAT GO:0005924~cell-substrate adherens junction 6 2.8E-02