TABLE 3.
Comparison of clinical outcomes between patients with mixed Candida/bacterial bloodstream infections (cases) and those with monomicrobial candidaemia (controls)
| Variables | Cases (n = 37) | Controls (n = 89) | p |
|---|---|---|---|
| Documented clearance of candidaemia within 3 days after initiation of antifungal therapya | 19/30 (63) | 48/57 (84) | 0.035 |
| Treatment failure at 2 weeks | 25 (68) | 55 (62) | 0.55 |
| Clinical failureb | 5 (14) | 13 (15) | 1.00 |
| Microbiological failurec | 5 (14) | 5 (6) | 0.16 |
| Death | 15 (41) | 37 (42) | 1.00 |
| Mortality at 6 weeks | |||
| Crude | 24 (65) | 50 (56) | 0.43 |
| Candidaemia-attributable | 16 (43) | 37 (42) | 1.00 |
Data are no. (%) of patients, unless otherwise indicated.
a
Data are event/evaluable no. (%) of patients.
b
Worsening or no improvement of attributable symptoms or signs of candidaemia.
c
Persistent isolation of Candida species from blood specimens at 2 weeks.