Figure 1.

Dectin-1 expression was induced in a human monocyte (THP-1) cell line by LPS. (a) Dectin-1 RT-qPCR demonstrated increased expression of mRNA in THP-1 cells at 2 and 24 h after LPS stimulation. The expression was also increased at the time points with GM-CSF and IL-4. (b) Cell surface dectin-1 was increased with LPS stimulation in a dose-dependent manner. (c) The percentage of cells with higher level of dectin-1 expression by FACS analysis. The results were representative of 2 independent experiments.