Figure 1. Demographic information, distribution by age of initial symptom, and cumulative symptoms during the first month of the disease.
Panel A: Patient’s age at disease onset
Panel B: Symptom presentation according to patients’ age (age <12 = 111 patients; 12-17 years = 99; ≥ 18 years = 364; 3 unknown). The frequency of abnormal behavior, movement disorder, and seizures is different among the three age groups (p<0·0001)
Panel C: Distribution by age of cumulative symptoms during the first month of the disease. For each color, the first dark column refers to patients < 12 years, the middle column to patients 12-17 years, and the right, light column to patients ≥ 18 years. *p = 0·002; **p < 0·0005; #p = 0·024.