Table 1.

Number and severity of symptoms during the first month of the disease

(n = 571)#		Non-tumor		Tumor		All
number of symptoms *	8	28	8%	24	11%	52	9%	0·37 **
	7	64	18%	48	22%	112	20%
	6	72	20%	52	24%	124	22%
	5	70	20%	37	17%	107	19%
	4	72	20%	31	14%	103	18%
	3	34	10%	13	6%	47	8%
	2	10	3%	10	5%	20	4%
	1	5	1%	1	0%	6	1%
maximum mRS	5	296	84%	199	91%	495	87%	0·086 †
	4	49	14%	19	9%	68	12%
	3	6	2%	1	0%	7	1%
	Unknown	1		0		1
ICU	Yes	248	71%	187	85%	435	77%	< 0·0001 ‡
	No	100	29%	32	15%	132	23%
	Unknown	4		4		4

^#Clinical information was insufficiently detailed in six patients.

^*The eight symptom categories are: behavior/cognition, memory dysfunction, speech disorder/mutism, seizures, decrease in level of consciousness, movement disorder, autonomic dysfunction and central hypoventilation.

^**Fisher Exact test: 1-3 vs 4-8 symptoms, comparing non-tumor and tumor patients.

^†Fisher-Freeman-Halton test

^‡Fisher Exact test

mRS = modified Rankin Scale; ICU = intensive care unit