Table 1.
Number and severity of symptoms during the first month of the disease
(n = 571)# | Non-tumor | Tumor | All | |||||
---|---|---|---|---|---|---|---|---|
number of symptoms * | 8 | 28 | 8% | 24 | 11% | 52 | 9% | 0·37 ** |
7 | 64 | 18% | 48 | 22% | 112 | 20% | ||
6 | 72 | 20% | 52 | 24% | 124 | 22% | ||
5 | 70 | 20% | 37 | 17% | 107 | 19% | ||
4 | 72 | 20% | 31 | 14% | 103 | 18% | ||
3 | 34 | 10% | 13 | 6% | 47 | 8% | ||
2 | 10 | 3% | 10 | 5% | 20 | 4% | ||
1 | 5 | 1% | 1 | 0% | 6 | 1% | ||
maximum mRS | 5 | 296 | 84% | 199 | 91% | 495 | 87% | 0·086 † |
4 | 49 | 14% | 19 | 9% | 68 | 12% | ||
3 | 6 | 2% | 1 | 0% | 7 | 1% | ||
Unknown | 1 | 0 | 1 | |||||
ICU | Yes | 248 | 71% | 187 | 85% | 435 | 77% | < 0·0001 ‡ |
No | 100 | 29% | 32 | 15% | 132 | 23% | ||
Unknown | 4 | 4 | 4 |
Clinical information was insufficiently detailed in six patients.
The eight symptom categories are: behavior/cognition, memory dysfunction, speech disorder/mutism, seizures, decrease in level of consciousness, movement disorder, autonomic dysfunction and central hypoventilation.
Fisher Exact test: 1-3 vs 4-8 symptoms, comparing non-tumor and tumor patients.
Fisher-Freeman-Halton test
Fisher Exact test
mRS = modified Rankin Scale; ICU = intensive care unit