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. Author manuscript; available in PMC: 2014 Feb 1.

Published in final edited form as: Am J Transplant. 2012 Dec 27;13(2):299–311. doi: 10.1111/ajt.12016

rPSGL-1-Ig therapy reduces macrophage and CD45+ accumulation in the allograft in response to MHC I antibody. Native or transplanted hearts were assessed immunohistochemically for Mac-2 (a) or CD45 (b) and staining was scored by a pathologist blinded to the experimental groups. Global ANOVA and individual comparisons * p<0.05. *** p<0.001. Graphs show the distribution of scores for each group. Representative micrographs at 100x and 200x magnification of Mac-2 staining and H&E are shown in (c)

rPSGL-1-Ig therapy reduces macrophage and CD45+ accumulation in the allograft in response to MHC I antibody. Native or transplanted hearts were assessed immunohistochemically for Mac-2 (a) or CD45 (b) and staining was scored by a pathologist blinded to the experimental groups. Global ANOVA and individual comparisons * p<0.05. *** p<0.001. Graphs show the distribution of scores for each group. Representative micrographs at 100x and 200x magnification of Mac-2 staining and H&E are shown in (c)