. Author manuscript; available in PMC: 2013 May 1.

Published in final edited form as: Biochim Biophys Acta. 2011 Oct 25;1821(5):843–851. doi: 10.1016/j.bbalip.2011.10.011

Table 2.

Effect of eliminating FA sources on plasma TG

TG precursor	control		HTG		HTG + T2D
TG precursor	TG (mg/dL)	% reduction	TG (mg/dL)	% reduction	TG (mg/dL)	% reduction
All sources	62	-	179	-	191	-
Eliminate:
NEFA	3	-95%	32	-82%	43	-78%
de novo lipogenesis	60	-3%	153	-15%	171	-10%
Diet	60	-3%	173	-3%	167	-13%

Vedala et al[46] studied the relative contribution of various FA sources to VLDL-TG. They report the plasma TG and the absolute contribution of each FA source to VLDL-TG synthesis, which was measured during tracer kinetics study and reported in g/day. We used the reported parameters to estimate the reduction in serum TG that would correspond to the elimination of each FA source, assuming no change in TG clearance.