Table 2.
Main maternal and perinatal outcomes. Values are numbers (percentages) unless stated otherwise
| Vaccinated H1N1 (n=7293) | Non-vaccinated H1N1 (n=23 195) | P value | |
|---|---|---|---|
| Maternal outcomes | |||
| Hospital admission during pregnancy | 548 (7.5) | 1471 (6.3) | 0.002 |
| Pregnancy induced hypertension | 288 (3.9) | 833 (3.6) | NS |
| Pre-eclampsia | 124 (1.7) | 384 (1.7) | NS |
| Eclampsia | 16 (0.2) | 66 (0.3) | NS |
| Haemorrhage during pregnancy: | |||
| First trimester | 128 (1.8) | 278 (1.2) | 0.01 |
| Second trimester | 54 (0.7) | 134 (0.6) | |
| Third trimester | 49 (0.7) | 157 (0.7) | |
| Peripartum haemorrhage: | |||
| Antepartum | 25 (0.3) | 134 (0.6) | NS |
| Intrapartum | 12 (0.2) | 33 (0.1) | |
| Postpartum | 38 (0.5) | 92 (0.4) | |
| Maternal admission to intensive care | 17 (0.2) | 67 (0.3) | NS |
| Mode of delivery: | |||
| Vaginal | 5180 (71.0) | 16 900 (72.9) | 0.02 |
| Forceps/vacuum | 68 (0.9) | 228 (1.0) | |
| Caesarean section | 2039 (28.0) | 6022 (26.0) | |
| Perinatal outcomes | |||
| Primary composite outcome | 513 (7.0) | 2160 (9.3) | <0.01 |
| Preterm births (<37 weeks) | 354 (4.9) | 1505 (6.5) | <0.01 |
| Low birth weight | 357 (4.9) | 1606 (6.9) | <0.01 |
| Very low birth weight | 44 (0.6) | 306 (1.3) | <0.01 |
| Fetal mortality | 25 (0.3) | 111 (0.5) | 0.08 |
| Early neonatal mortality (from birth to day 7) | 29 (0.4) | 146 (0.6) | <0.01 |
| Perinatal mortality | 54 (0.7) | 257 (1.1) | <0.01 |
| Apgar score <7 at 5 minutes | 28 (0.4) | 127 (0.5) | 0.018 |
| Admission to neonatal intensive care | 433 (5.9) | 1523 (6.6) | NS |
| Fetal malformations | 35 (0.5) | 137 (0.6) | NS |
| Non-immune jaundice | 273 (3.7) | 706 (3.0) | 0.012 |
NS=non-significant.