Table 3.
Health-related utilities and utility decrements
| Parameter | Value | 95% CI/SE |
|---|---|---|
| Utility in severe COPDa | 0.751 | 0.738–0.765 |
| Utility in very severe COPDa | 0.657 | 0.635–0.678 |
| Utility decrement (annual) associated | 0.010 | SE = 0.007 |
| with community-treated exacerbationb | ||
| Utility decrement (annual) associated | 0.042 | SE = 0.009 |
| with hospital-treated exacerbationsb |
Notes:aData on file, Takeda Pharma AG, Pfäffikon, Switzerland, 2010;5
b
utility decrements are based on Rutten-van Mölken et al14 and the values represent utility loss over 1 year; the loss of utility attributed to 1-month model cycle length is estimated as: 0.01 × 12 = 0.12 and 0.042 × 12 = 0.504.
Abbreviations: 95% CI, 95% confidence interval; COPD, chronic obstructive pulmonary disease; SE, standard error.