TABLE III.
Z-Scores for Growth Parameters: Median (5th, 95th Centiles); n = Number of Participants
| Entire cohort | Deletions
|
UPD/imprinting defects | UBE3A | |||
|---|---|---|---|---|---|---|
| Class I | Class II | All | ||||
| Birth weight | 0.24 (−1.42, 1.55) (n = 91) |
0.10 (−1.90, 0.79) (n = 29) |
0.23 (−1.47, 2.25) (n = 34) |
0.18 (−1.66, 1.42) (n = 67) |
0.50 (−0.56, 2.14) (n = 13) |
0.23 (−1.11, 0.59) (n = 11) |
| Birth length | 0.55 (−1.74, 2.58) (n = 73) |
−0.02 (−2.41, 2.51) (n = 21) |
0.54 (−1.97, 2.55) (n = 26) |
0.31 (−2.32, 2.55) (n = 50) |
1.06 (0.08, 2.85) (n = 12) |
−0.32 (−1.18, 2.09) (n = 11) |
| Weight | −0.27 (−2.50, 2.17) (n = 92) |
−0.91* (−2.59, 0.34) (n = 29) |
−0.45 (−2.17, 1.38) (n = 35) |
−0.53* (−2.58, 1.08) (n = 68) |
1.61* (0.64, 3.16) (n = 13) |
−0.20 (−1.72, 2.12) (n = 11) |
| Length or Height | 0.04 (−1.76, 1.84) (n = 92) |
−0.18 (−1.82, 0.73) (n = 29) |
0.20 (−1.76, 1.75) (n = 35) |
−0.01 (−1.90, 1.48) (n = 68) |
0.19 (−0.84, 2.87) (n = 13) |
−0.06 (−1.11, 1.77) (n = 11) |
| Body mass index | −0.35 (−2.97, 2.14) (n = 92) |
−0.63 (−3.35, 0.69) (n = 29) |
−0.61 (−2.65, 0.99) (n = 35) |
−0.60* (−3.18, 0.84) (n = 68) |
1.36* (1.06, 3.03) (n = 13) |
0.28 (−1.93, 2.26) (n = 11) |
| Head circumference | −2.59* (−4.63, −0.61) (n = 92) |
−3.05* (−4.50, −1.46) (n = 29) |
−2.83* (−4.64, −1.49) (n = 35) |
−2.85* (−4.66, −1.46) (n = 68) |
−1.41* (−2.61, −0.43) (n = 13) |
−1.99 (−3.46, −0.10) (n = 11) |
UPD, uniparental disomy.
a
P < 0.001 compared to the general population (i.e., median z-score of 0).