. Author manuscript; available in PMC: 2013 Jul 1.

Published in final edited form as: Bioorg Med Chem. 2012 May 10;20(13):4140–4148. doi: 10.1016/j.bmc.2012.04.055

Table 4.

Kinetics parameters for the tetra-peptide substrate and compound 7n against WNV NS2B/NS3pro at 37 °C

[7n]	K_m	k_cat	k_cat/K_m

μM	μM	s^-1	M^-1·s^-1
0	24.01 ± 0.62	0.060 ± 0.0013	2499 ± 99
1	26.04 ± 0.75	0.059 ± 0.0014	2274 ± 100
3	34.16 ± 1.88	0.062 ± 0.0018	1811 ± 163
5	36.90 ± 2.36	0.055 ± 0.0020	1503 ± 162