Table 1.
Virus | Protein | Site of Insertion1 | Biotinylated?2 | Replication Competence2 | Notes2 |
---|---|---|---|---|---|
HIV-1 | MA | 120 | Yes | ++++ | |
IN | 5 | No | - | Unstable IN | |
176 | No | - | No infectious virus | ||
212 | ND | - | No infectious virus | ||
247 | ND | - | No infectious virus | ||
2893 | Yes | +/- | |||
HIV-2 | Vpr | 1 | Yes | ++++ | |
Vpx | 71 | Yes | ++++ | ||
112 | Yes | ++++ |
Amino acid immediately prior to insertion
Data not shown for IN-5 and -176; IN-212 & -247 previously reported in (Belshan et al., 2009)
Clone referred to as NLXINB in text