Table 3.
Numbers of reads per million mapping to known canine MHC genes, summarised for the various tissues plus the combined assembly (see Methods for details)
| Class | Gene | Reference | Chromosome in dog |
Tissue |
Combined | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Heart | Intestine | Kidney | Lung | Skin | Spleen | Testis | ||||||
| I |
DLA-64 |
ENSCAFG00000000500 |
12 |
78.4 |
257.1 |
324.8 |
390.2 |
85.2 |
687.6 |
61.5 |
240.7 |
|
| I |
DLA-79 |
ENSCAFG00000008234 |
18 |
0.0 |
0.0 |
14.9 |
0.0 |
15.6 |
3.6 |
0.0 |
10.5 |
|
| I |
DLA-88 Precursor |
ENSCAFG00000000487 |
12 |
0.0 |
269.1 |
268.2 |
451.5 |
43.6 |
654.8 |
61.5 |
210.3 |
|
| I |
DLA-88 |
ENSCAFG00000000492 |
12 |
78.4 |
191.4 |
283.1 |
550.9 |
1.0 |
753.0 |
71.7 |
207.8 |
|
| I |
Tapasin |
ENSCAFG00000000972 |
12 |
0.0 |
41.9 |
110.2 |
91.8 |
2.1 |
149.2 |
30.7 |
50.8 |
|
| II |
BTNL2 |
ENSCAFG00000000797 |
12 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
|
| II |
CD74 |
ENSCAFG00000018101 |
4 |
52.3 |
71.8 |
143.0 |
145.4 |
0.0 |
338.3 |
41.0 |
88.7 |
|
| II |
DLA-DRA |
ENSCAFG00000000803 |
12 |
26.1 |
59.8 |
134.1 |
298.4 |
165.2 |
516.6 |
20.5 |
198.3 |
|
| II |
DQ Alpha precursor |
ENSCAFG00000000812 |
12 |
0.0 |
6.0 |
65.6 |
168.3 |
83.1 |
247.4 |
10.2 |
96.7 |
|
| II |
HLA-DMA |
ENSCAFG00000000848 |
12 |
0.0 |
0.0 |
3.0 |
0.0 |
1.0 |
7.3 |
0.0 |
2.0 |
|
| II |
HLA-DOA |
ENSCAFG00000000896 |
12 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
3.6 |
20.5 |
1.5 |
|
| II |
HLA-DOB |
ENSCAFG00000000819 |
12 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
|
| II |
HLA-DPB1 |
ENSCAFG00000000900 |
12 |
0.0 |
0.0 |
3.0 |
0.0 |
3.1 |
0.0 |
0.0 |
2.0 |
|
| II |
HLA-DQB1 |
ENSCAFG00000000814 |
12 |
0.0 |
17.9 |
26.8 |
53.6 |
6.2 |
54.6 |
10.2 |
20.4 |
|
| II |
HLA-DRB1 |
ENSCAFG00000000806 |
12 |
52.3 |
59.8 |
83.4 |
336.7 |
40.5 |
232.8 |
51.2 |
95.7 |
|
| II |
IK cytokine |
ENSCAFG00000005869 |
2 |
52.3 |
6.0 |
62.6 |
38.3 |
128.9 |
36.4 |
61.5 |
84.2 |
|
| II |
RFX3 |
ENSCAFG00000002053 |
1 |
0.0 |
47.8 |
8.9 |
0.0 |
0.0 |
0.0 |
61.5 |
8.5 |
|
| III |
BAG6 |
ENSCAFG00000000575 |
12 |
130.7 |
131.6 |
122.2 |
122.4 |
4.2 |
80.0 |
706.9 |
89.2 |
|
| III |
HSP70 |
ENSCAFG00000000641 |
12 |
2117.7 |
998.7 |
2413.4 |
7789.6 |
83.1 |
4565.6 |
624.9 |
1730.3 |
|
| III |
LTA |
ENSCAFG00000000515 |
12 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
0.0 |
|
| III |
TNF |
ENSCAFG00000000517 |
12 |
0.0 |
0.0 |
0.0 |
7.7 |
0.0 |
0.0 |
0.0 |
0.5 |
|
| |
|
|
Total class I |
156.9 |
759.5 |
1001.1 |
1484.5 |
147.6 |
2248.2 |
225.4 |
720.1 |
|
| |
|
|
Total class II |
183.0 |
269.1 |
530.4 |
1040.7 |
428.1 |
1437.0 |
276.6 |
598.0 |
|
| |
|
|
Total class III |
2248.4 |
1130.2 |
2535.6 |
7919.7 |
87.3 |
4645.6 |
1331.9 |
1820.0 |
|
| Grand total | 2588.3 | 2158.8 | 4067.1 | 10444.8 | 663.0 | 8330.8 | 1833.9 | 3138.1 | ||||