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. 2013 Jan 23;14:12. doi: 10.1186/1471-2350-14-12

Table 8.

Individual and interactive effects of SIM2 and ETS2 SNPs in different malignant groups (analyzed by MDR 2.0 beta 8.1)

 
Interactive effects
SNP ID (individual effect) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
ALL
rs2073601 (3.69)
-
−4.91
−3.23
−1.16
−0.45
−3.42
−1.34
−1.41
−2.55
−2.33
−2.33
−2.45
−2.45
−2.13
−4.27
rs2073416 (2.95)
 
-
−1.55
−1.00
−1.97
−2.21
−1.99
−2.25
−2.44
−1.98
−1.98
−2.12
−2.12
−1.58
−3.53
rs2269188 (2.56)
 
 
-
0.74
−0.29
−0.01
0.79
0.16
−0.47
−0.25
−0.25
−0.22
−0.22
−0.31
−2.15
rs461155 (0.07)
 
 
 
-
0.21
−0.53
−0.37
0.30
−0.63
−0.39
−0.39
−0.21
−0.21
−0.29
−0.65
rs1051425 (0.65)
 
 
 
 
-
−0.31
−0.13
−0.52
−0.06
0.18
0.18
0.07
0.07
−0.26
−0.74
rs374575 (1.03)
 
 
 
 
 
-
−1.08
−1.18
−1.15
−1.14
−1.14
−0.89
−0.89
−1.06
−0.69
rs2070529 (0.73)
 
 
 
 
 
 
-
−1.04
−0.91
−0.16
−0.16
0.48
0.48
0.91
−1.15
rs2070530 (0.64)
 
 
 
 
 
 
 
-
−1.10
−0.90
−0.90
0.15
0.15
1.87
−1.06
rs2070531 (0.95)
 
 
 
 
 
 
 
 
-
−1.13
−1.13
1.44
1.44
2.53
−1.23
rs6517481 (0.58)
 
 
 
 
 
 
 
 
 
-
−1.09
2.21
2.21
2.90
−1.00
rs7276961 (0.58)
 
 
 
 
 
 
 
 
 
 
-
2.21
2.21
2.90
−1.00
rs1051475 (0.39)
 
 
 
 
 
 
 
 
 
 
 
-
−0.57
2.52
−0.97
rs1051476 (0.39)
 
 
 
 
 
 
 
 
 
 
 
 
-
2.52
−0.97
rs11254 (0.63)
 
 
 
 
 
 
 
 
 
 
 
 
 
-
−0.97
rs711 (3.55)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
-
BC
rs2073601 (3.50)
-
−4.62
−3.32
−3.69
3.32
−3.33
−3.89
−3.12
−3.03
−2.66
−2.66
−1.97
−1.97
−0.76
−3.03
rs2073416 (2.17)
 
-
−2.10
−2.36
−1.86
−1.78
−4.05
−3.14
2.60
2.47
2.47
1.90
1.90
−0.80
−1.56
rs2269188 (0.92)
 
 
-
−2.70
1.66
0.07
−1.09
−0.14
−2.90
−2.77
−2.77
−0.96
−0.96
−1.45
0.02
rs461155 (15.15)
 
 
 
-
−0.77
−3.55
−3.99
−3.22
−4.20
−4.07
−4.07
−1.19
−1.19
−1.31
−7.00
rs1051425 (0.58)
 
 
 
 
-
−2.71
−1.57
−0.97
−0.97
−1.50
−1.50
0.37
0.37
−0.66
−1.16
rs374575 (4.04)
 
 
 
 
 
-
−5.88
−5.44
−3.83
−4.28
−4.28
−2.39
−2.39
−2.19
−3.01
rs2070529 (3.79)
 
 
 
 
 
 
-
−5.97
−3.87
−5.35
−5.35
−1.63
−1.63
−0.79
−2.14
rs2070530 (3.03)
 
 
 
 
 
 
 
-
−4.90
−5.15
−5.15
−1.54
−1.54
0.33
−1.63
rs2070531 (4.01)
 
 
 
 
 
 
 
 
-
−4.91
−4.91
2.19
2.19
3.81
−2.37
rs6517481 (3.88)
 
 
 
 
 
 
 
 
 
-
−5.09
0.86
0.86
3.94
−1.95
rs7276961 (3.88)
 
 
 
 
 
 
 
 
 
 
-
0.86
0.86
3.94
−1.95
rs1051475 (1.00)
 
 
 
 
 
 
 
 
 
 
 
-
−1.23
7.32
0.19
rs1051476 (1.00)
 
 
 
 
 
 
 
 
 
 
 
 
-
7.32
0.19
rs11254 (1.12)
 
 
 
 
 
 
 
 
 
 
 
 
 
-
−1.36
rs711 (4.56)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
-
OC
rs2073601 (2.04)
-
−0.91
−1.51
−2.04
−0.62
−1.12
−0.79
−0.79
−1.14
−1.27
−1.27
−1.46
−1.46
−1.38
−2.44
rs2073416 (0.04)
 
-
0.21
−0.41
−0.25
−1.23
0.24
1.00
−0.58
−0.37
−0.37
1.27
1.27
0.42
−1.05
rs2269188 (0.81)
 
 
-
−1.17
0.45
−0.52
−0.49
−0.35
−0.97
−0.94
−0.94
−0.17
−0.17
−0.26
−1.31
rs461155 (13.14)
 
 
 
-
−0.70
−1.58
−0.64
−0.38
−1.83
−1.69
−1.69
0.38
0.38
−0.47
−1.26
rs1051425 (0.34)
 
 
 
 
-
−1.38
−0.77
−0.76
−1.37
−1.07
−1.07
−0.05
−0.05
−0.20
−1.23
rs374575 (1.89)
 
 
 
 
 
-
−2.33
−2.23
−1.45
−1.50
−1.50
−1.56
−1.56
−0.97
−2.66
rs2070529 (1.16)
 
 
 
 
 
 
-
−1.34
−1.78
−1.47
−1.47
−1.05
−1.05
−0.35
−1.52
rs2070530 (0.91)
 
 
 
 
 
 
 
-
−1.68
−1.31
−1.31
−1.92
−1.92
−0.44
−1.63
rs2070531 (1.47)
 
 
 
 
 
 
 
 
-
−2.48
−2.48
1.90
1.90
0.67
−2.13
rs6517481 (1.33)
 
 
 
 
 
 
 
 
 
-
−2.40
−1.46
−1.46
0.03
−1.99
rs7276961 (1.33)
 
 
 
 
 
 
 
 
 
 
-
−1.46
−1.46
0.03
−1.99
rs1051475 (0.48)
 
 
 
 
 
 
 
 
 
 
 
-
−0.69
1.33
−0.73
rs1051476 (0.48)
 
 
 
 
 
 
 
 
 
 
 
 
-
1.33
−0.73
rs11254 (0.11)
 
 
 
 
 
 
 
 
 
 
 
 
 
-
−0.51
rs711 (2.26)                             -

1 = rs2073601, 2 = rs2073416, 3 = rs2269188, 4 = rs461155, 5 = rs1051425, 6 = rs374575, 7 = rs2070529, 8 = rs2070530, 9 = rs2070531, 10 = rs6517481, 11 = rs7276961, 12 = rs1051475, 13 = rs1051476, 14 = rs11254, 15 = rs711 (Entropy values mentioned in bold are in synergistic interaction).