Table 1.
Biperiden (mg.kg-1body mass, p.o.) |
Conventional pigs |
Göttingen minipigs |
Conventional pigs |
Göttingen minipigs |
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---|---|---|---|---|---|---|---|---|
Working memory | Reference memory | |||||||
0.05 |
t8 = 0.36 |
p = 0.7318 |
t8 = 2.05 |
p = 0.0796 |
t8 = 1.18 |
p = 0.2765 |
t8 = 0.34 |
p = 0.7425 |
0.15 |
t8 = -0.24 |
p = 0.8157 |
t8 = 1.63 |
p = 0.1477 |
t8 = 0.09 |
p = 0.9332 |
t8 = -0.66 |
p = 0.5277 |
1.5 |
t8 = 0.39 |
p = 0.7055 |
t8 = 0.55 |
p = 0.5983 |
t8 = -1.43 |
p = 0.1966 |
t8 = 0.27 |
p = 0.7986 |
5 |
t8 = 0.14 |
p = 0.8916 |
t8 = -0.62 |
p = 0.5577 |
t8 = -2.96 |
p = 0.0212 |
t8 = -4.75 |
p = 0.0021 |
15 |
t7 = -0.46 |
p = 0.6585 |
t8 = -0.41 |
p = 0.6975 |
t7 = -2.41 |
p = 0.0528 |
t8 = -0.22 |
p = 0.8316 |
20 |
n.t. |
t8 = -2.50 |
p = 0.0412 |
n.t. |
t8 = -3.55 |
p = 0.0094 |
||
|
Trial duration |
Latency to first rewarded hole visit |
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0.05 |
t8 = -0.81 |
p = 0.4427 |
t8 = -1.31 |
p = 0.2325 |
t8 = -1.00 |
p = 0.3519 |
t8 = -1.25 |
p = 0.2522 |
0.15 |
t8 = 0.89 |
p = 0.4032 |
t8 = -1.45 |
p = 0.1895 |
t8 = 0.08 |
p = 0.9375 |
t8 = 0.29 |
p = 0.7797 |
1.5 |
t8 = -0.49 |
p = 0.6358 |
t8 = -0.78 |
p = 0.4612 |
t8 = -1.18 |
p = 0.2749 |
t8 = -0.74 |
p = 0.4831 |
5 |
t8 = 4.27 |
p = 0.0037 |
t8 = 0.21 |
p = 0.8401 |
t8 = -1.63 |
p = 0.1476 |
t8 = -1.98 |
p = 0.0876 |
15 |
t7 = 1.55 |
p = 0.1725 |
t8 = 2.05 |
p = 0.0792 |
t7 = -3.00 |
p = 0.0241 |
t8 = -1.57 |
p = 0.1614 |
20 | n.t. | t8 = 1.98 | p = 0.0887 | n.t. | t8 = -5.11 | p = 0.0014 |
One-sample t-statistics and the associated p-values of the difference scores between the control sessions preceding treatment and the corresponding treatment sessions are tabulated. Abbreviation: n.t. not tested, because none of the conventional pigs consumed the entire dose of 20 mg.kg-1. p-values < 0.05 are printed bold and italicized, p-values between 0.05 and 0.1 (marginal effects) are italicized.