Table 3. Summary of cytokine secretion profiles in the Cytokine-driven assay.
Subject | Antigen | Epitope | Secreted Cytokine | ||||||||
IL-4 | IL-5 | IL-10 | IL-13 | IL-17 | IL-21 | TNF-α | IFN-γ | ||||
HS#2 | GAD65 | p66 | – | – | + | + | – | – | + | + | |
ZnT8 | p2 | + | + | + | + | – | – | + | + | ||
p18 | + | + | + | + | – | – | – | + | |||
p33 | + | + | – | + | – | – | – | + | |||
p93 | + | – | – | + | – | – | + | + | |||
HS#3 | GAD65 | p73 | – | + | + | + | – | – | – | + | |
ZnT8 | p2 | + | + | – | + | – | – | – | + | ||
p18 | + | + | + | + | – | – | – | + | |||
HS#4 | GAD65 | p73 | – | – | – | + | – | – | – | + | |
ZnT8 | p18 | – | – | – | + | – | – | – | + | ||
p65 | + | + | – | + | – | – | – | + | |||
p68 | – | + | – | + | – | – | – | + | |||
HS#7 | ZnT8 | p65 | – | + | – | + | – | – | – | + | |
p68 | – | – | – | + | – | – | – | + | |||
p87 | – | – | – | + | – | – | – | + |
HS, healthy subject; p, peptide.