Table 2.
Selected SNPs for genotyping
| Gene | SNP number | SNP position | Allele [major/minor] | Function |
|---|---|---|---|---|
|
OPG |
rs3102735 |
chr8: 119965070 |
T/C |
Transition substitution (5’ near region) |
|
OPG |
rs2073618 |
chr8: 119964052 |
G/C |
Missense (p.K3N) |
|
RANK |
rs1805034 |
chr18: 60027241 |
T/C |
Missense (p.V192A) |
|
RANK |
rs35211496 |
chr18: 60021761 |
C/T |
Missense (p.H141Y) |
|
RANKL |
rs9533156 |
chr13: 43147671 |
T/C |
Transition substitution (5’ near region) |
|
RANKL |
rs2277438 |
chr13: 43155168 |
A/G |
Transition substitution (intron1/exon2 boundary) |
| RANKL | rs1054016 | chr13: 43182002 | G/T | Transversion substitution (3’ UTR) |
RANK = receptor activator of nuclear factor-κB; RANKL = RANK ligand; SNP = single nucleotide polymorphism; OPG = osteoprotegerin.