Table 1.

Characteristics of patients with acute schistosomiasis fulfilling the inclusion criteria

Patient	Region of exposure	Reason for travel	Incubation time [days](1)	Time to diagnosis [days](2)	Eosinophils absolute[per μl]	PCR	Serology	Microscopy
1	Rwanda	Tourist	57	62	5.400	pos	pos	S.m.
2	Rwanda	Tourist	33	54	2.090	pos	(pos)	S.m.
3	Mozambique	Occupational	28	42	2.860	pos	pos	Ø
4	Ethiopia	Occupational	27	43	2.650	pos	Ø	Ø
5	Uganda	Occupational	38	56	1.920	pos	pos	Ø
6	Uganda	Occupational	20	32	1.600	pos	pos	n.a.
7	Malawi	Tourist	18	20	1.050	pos	pos	n.a.
8	Mozambique	Tourist	35	56	33.050	pos	Ø	n.a.
9	Yemen	Tourist	40	54	1.540	pos	pos	Ø
10	Malawi	Tourist	27	35	980	pos	Ø	Ø
11(3)	Kenya	Tourist	94	96	3.220	Ø	pos	Ø
12	Kenya	Tourist	184	302	1.100	pos	pos	Ø
13	Sudan	Occupational	27	33	3.350	pos	Ø	Ø
14	Tanzania	Volunteer	75	88	5.880	pos	pos	n.a.
15	East Africa	Volunteer	127	131	1.760	pos	pos	Ø
16(4)	Kenya	VFR	150	210	n.a.	pos	n.a.	S.m.
17	Uganda	Tourist	24	27	n.a.	pos	pos	n.a.
18	Malawi	Tourist	31	73	3.920	pos	Ø	n.a.
19	East Africa	Volunteer	32	104	4.010	pos	pos	Ø
20	Malawi	Tourist	31	34	1.780	Ø	Ø	Ø
21	Mali	Occupational	23	32	1.140	pos	Ø	Ø
22	Tanzania	Volunteer	62	66	2.800	pos	Ø	Ø
23	Madagascar	Tourist	35	38	2.640	pos	pos	n.a.
24	Madagascar	Occupational	92	261	890	pos	pos	n.a.
25	Madagascar	Occupational	122	152	870	pos	pos	Ø
26	East Africa	Tourist	24	36	3.150	pos	pos	Ø
27	Tanzania	Volunteer	47	76	1.700	pos	pos	S.m.
28	Tanzania	Volunteer	47	80	9.850	pos	pos	Ø
29	Tanzania	Volunteer	62	94	2.310	pos	pos	Ø
30	Tanzania	Volunteer	97	196	2.290	Ø	pos	Ø
31	Madagsacar	Occupational	n.a.	160	1.100	pos	pos	Ø
32	Madagascar	Tourist	17	43	1.020	pos	pos	S.m.
33(5)	Ghana	VRF	31	69	1.200	pos	pos	n.a.
34	Madagascar	Tourist	23	34	1.210	pos	pos	n.a.
35	Uganda	Tourist	41	53	2.900	pos	Ø	n.a.
36	Madagascar	Tourist	25	42	23.300	pos	pos	S.m.
37	Ghana	Tourist	40	46	1.660	pos	pos	n.a.
38	Tanzania	Tourist	27	119	2.340	pos	pos	n.a.

(1): Time from exposure to beginning of clinical symptoms.

(2): Time from exposure to diagnostics.

(3): Less than 2 ml of Serum was available for DNA extraction.

(4): Patient evaluated for liver transplantation due to known Hepatitis B Virus infection and eosinophilia after visiting her family.

(5): Patient with meningitis and eosinophils in cerebrospinal fluid, Schistosoma DNA detected by PCR in cerebrospinal fluid.

VFR Visiting relatives and friends.

n.a. Not available.

pos Positive.

Ø Negative.

(pos) Only one of two different serological tests for schistosomiasis shows a positive result.

S.m. eggs of S.mansoni.