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. 2013 Feb 4;8(2):e52554. doi: 10.1371/journal.pone.0052554

Figure 1. F9 versus F9Inline graphic.

Figure 1

Cross sections of a F9 WT aggregate (A) and of a F9Inline graphic aggregate (B). The staining is for Inline graphic-catenin, scale bars, 10 Inline graphic. (C) Schematic representation of the cortical contractions at the cell-extracellular medium interface (Inline graphic), at the cell-cell interface (Inline graphic) and of the adhesion energy J. Inline graphic and Inline graphic increase the tissue surface tension, whereas Inline graphic decreases it (see Eq. 2). (D) Closer view of two F9Inline graphic cells in contact. The difference between the interfacial tensions at the cell-cell Inline graphic and cell-extracellular medium Inline graphic interfaces gives the aggregate surface tension (Inline graphic). Inline graphic increases the surface tension whereas Inline graphic decreases it. Scale bar, 5 Inline graphic. (E-F) Cartoons of cell-cell contacts in the case of F9 WT cells (E) and F9Inline graphic cells (F). The presence of Inline graphic-catenin at cell-cell junction is described as a catalyzer for actin reorganization at cell-cell junctions.