Skip to main content
. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Expert Rev Med Devices. 2013 Jan;10(1):125–134. doi: 10.1586/erd.12.62

Figure 3. Description of an in vivo photoacoustic flow cytometer.

Figure 3

The principle of operation for the detection of melanoma circulating tumor cells (A), the instrumentation set up (B), the in vivo experimental set up (C) and image of a mouse ear blood vessel and the laser beam (D), an image of a melanoma cell within the vessel (E) and the resulting photoacoustic signals (F) from blood (left) from a single B16F10 melanoma cell within blood (middle), and the photoacoustic signal trace in the presence of a melanoma cell (right) (F) are all shown.

CCD: Charge-coupled device; NIR: Near-Infrared; PA: Photoacoustic; PC: Personal computer.

(A)&(B): Modified with permission from [87]. (C)–(F): Reproduced with permission from [87] © International Society for Advancement of Cytometry (2011).