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Chlorogenic acid protected against sepsis-induced mortality. Chlorogenic acid was administered at various doses after the induction of sepsis via an intraperitoneal injection of LPS or CLP. Mice were monitored for survival for up to 10 d. (A) LPS-injected mice were given chlorogenic acid or ethyl pyruvate. (B) CLP mice were given various doses of chlorogenic acid or ethyl pyruvate. The results of treatment groups were compared with the vehicle-treated group. n = 10–30 per group.
