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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: J Immunol. 2013 Jan 7;190(4):1447–1456. doi: 10.4049/jimmunol.1202115

Figure 6. λ1+ B cells are longer-lived in TLR9-deficient mice.

Figure 6

8-10 wk old mice were given 0.5 mg BrdU i.p. every 12 hours for 0, 2 or 4 days before sacrifice. (A) Splenic CD22+ CD93+ λ1+ transitional B cells, (B) splenic CD22+ CD21/35int CD23+ λ1+ FO B cells, or (C) axillary LN CD22+ λ1+ B cells were evaluated for BrdU incorporation by FACS. (D-F) BrdU incorporation in transitional, FO, and LN populations gated on λ1− cells. Data are pooled from 4 independent experiments, n=4-6 animals per timepoint and genotype.