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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Cancer Res. 2012 Dec 5;73(3):1245–1255. doi: 10.1158/0008-5472.CAN-12-3150

Figure 3. Increased histologic injury in Gpx3−/− colons.

Figure 3

A) Representative H&E staining from WT (10x top, 20x bottom left) or Gpx3−/− (10x top, 20x bottom right) colons. There is evidence for invasive adenocarcinoma in the Gpx3−/− tumor. B) Histologic injury score for DSS only or AOM/DSS tissues. ** P<0.01. C) Division of the histological injury scores from Fig. 3B into pathological inflammation, extent, and crypt damage/regeneration scores for DSS only or AOM/DSS tissues. ***P<0.001. D) Dysplasia grading (performed by MKW) in WT and Gpx3−/− tumors. Results represent percentage of total tumors for each group within each grade.