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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Biochem Biophys Res Commun. 2013 Jan 3;431(1):19–24. doi: 10.1016/j.bbrc.2012.12.114

Figure 1. Effects on osteoblastic gene expression.

Figure 1

Realtime RT-qPCR analysis of RNA isolated from calvarial bone for osteoblastic differentiation markers, (A) alkaline phosphatase (ALP), (B) BMP-2 and its target gene, Smad7, and Wnt target genes, Axin-2 and LEF-1, in Ldlr-/- and Ldlr-/-PON1tg mice treated with control vehicle or intermittent PTH for 4 weeks. Values were expressed as mean ± SEM. *p < 0.005 vs. Ldlr-/- (both control and PTH) and Ldlr-/-PON1tg control; §p < 0.01 vs. control Ldlr-/- and control Ldlr-/-PON1tg.