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. Author manuscript; available in PMC: 2014 Feb 15.
Published in final edited form as: J Immunol. 2013 Jan 7;190(4):1714–1724. doi: 10.4049/jimmunol.1202410

Figure 5. Effect of Nrf2 genotype on acid and gastric particulate aspiration-induced synergistic lung injury and inflammation.

Figure 5

BAL recovered from WT and Nrf2−/− mice 5 h following pulmonary injury, as described in Figure 3, were analyzed for: A) [albumin] (white inset bars within the acid+part. data represent predicted values if injury was additive); B) PMN alveolitis; and C) ratio of BAL [albumin] to # of recovered PMN, an indicator of the degree of lung injury/PMN. N = 6 – 9 for each group from 7 independent experiments. * P < 0.05 for comparisons indicated by the brackets, § P < 0.05 for synergistic interaction of acid and particulate components within the indicated genotype by 2-way ANOVA (i.e., WT or Nrf2−/− mice).