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Body weight of mice on HFD with or without treatment. Initial body weight of each mouse is taken for 100 percent. Change of the weight was determined once a week. 1: RD; 2: HFD; 3: HFD+resv (resveratrol); 4: HFD+Rapa (rapamycin); 5: HFD+Re+Ra (+resveratrol+rapamycin in combination). Data present mean±S.E.M. Statistically significant differences were assessed using Student's t-test
