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Effects of HFD and rapamycin on body weight: comparison of male and female mice. Body weight of each mouse was determined at the beginning of the experiment (0 weeks) and 13 weeks after the initiation of HFD, and treatment with rapamycin in females and males of similar age (42 and 38.3 weeks, respectively). Data present mean±S.E.M. Statistically significant differences were assessed using Student's t-test
