| Functions of downregulated immune response genes |
| 45321 |
Leukocyte activation |
MICA, CD8A, CD8B, ELF4, TLR4, ADA, CD74, CD93, CD2, FCER1G, CD4, SYK, IL4, KLF6, PTPRC, CD3D, IL8, CD3E, RELB, SLAMF7, CD40, LAT, LCK, CD79A, LCP2 |
| 6954 |
Inflammatory response |
CXCL1, ITGAL, TNF, TLR2, NFKB1, ITGB2, TLR4, CCL5, CD97, CCL20, KRT1, IL1B, IL1A, CEBPB, IL8, IL1RN, GRO3, CD40, CCL18, CD180, C8G, SCYA7, CCL13, CCR7, CYBB, CCR5, CRH, CD14 |
| 19882 |
Antigen processing and presentation |
HLA-DQB1, MICA, CD8A, HLA-DRB1, RELB, HLA-C, FCGRT, HLA-B, HLA-G, CD74, B2M, FCER1G, HLA-DPA1, HLA-DPB1, HLA-DOB, AP3B1, HLA-DRA |
| 46649 |
Lymphocyte activation |
IL4, PTPRC, KLF6, MICA, CD3D, CD8A, ELF4, CD3E, CD8B, RELB, CD40, SLAMF7, CD74, ADA, LCK, CD2, CD4, CD79A, SYK |
| 30097 |
Hemopoiesis |
IL4, PTPRC, KLF6, CD3D, LYN, HCLS1, RELB, IFI16, MYH9, CD164, CD74, LCK, CD4, SPIB, CD79A, MYST1, SYK, MYST3 |
| 52033 |
Pathogen-associated molecular pattern recognition |
PF4, CHIT1, TLR2, TLR4, SCYA7, CD14, PF4V1, CLP1, TICAM1, FPRL1, FPR1 |
| 6935 |
Chemotaxis |
IL4, CXCL1, C5AR1, IL8, GRO3, ITGB2, PF4, CCL5, CCL18, SCYB5, SCYA7, CCL13, CCR7, CCR5, PPBP, CCL20, IL1B, FCER1G, SYK |
| 42110 |
T-cell activation |
PTPRC, MICA, CD3D, CD8A, CD3E, CD8B, ELF4, RELB, CD74, ADA, LCK, CD2, CD4, SYK |
| 2274 |
Myeloid leukocyte activation |
LAT, IL8, CD93, RELB, FCER1G, TLR4, LCP2 |
| 50778 |
Positive regulation of immune response |
PTPRC, MICA, SLK, FYN, KRT1, TLR2, FCER1G, CD79A, C8G, SYK |
| 6959 |
Humoral immune response |
PSMB10, CD83, ST6GAL1, TNF, HLXB9, POU2F2, KRT1, AIRE, C8G |
| 1934 |
Positive regulation of phosphorylation |
TNF, CCND3, LYN, HCLS1, IL1B, CD4, SYK |
| 45087 |
Innate immune response |
CYBB, IL1R1, SARM1, CLP1, KRT1, TLR2, TLR4, SLAMF7, CD180, C8G |
| 2252 |
Immune effector process |
PTPRC, LAT, MICA, FCN2, KRT1, FCER1G, SLAMF7, CD74, C8G |
| 30593 |
Neutrophil chemotaxis |
IL8, FCER1G, IL1B, ITGB2, SYK |
| 7229 |
Integrin signaling |
LAT, ITGAL, ITGAX, ITGB2, MYH9, ITGAM, SYK |
| 45058 |
T-cell selection |
CD3D, CD4, CD74, SYK |
| 1816 |
Cytokine production |
IL4, CD4, ISGF3G, CD226, LCP2 |
| 6909 |
Phagocytosis |
CD93, FCN2, CLP1, FCER1G, CD14 |
| 2460 |
Somatic recombination for adaptive response |
IL4, RELB, FCER1G, TLR4, CD74, C8G |
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| Functions associated with upregulated immune response genes |
| 48545 |
Response to steroid hormones |
CEBPA, CAV1, HMGB2, PRKACA, CD24 |
| 42326 |
Negative regulation of phosphorylation |
CAV1, PRKACA, INHA |
| 6956 |
Complement activation |
C4B, C3, C2 |
| 10817 |
Regulation of hormone levels |
DHRS2, ACE, FKBP1B |
| 43434 |
Response to peptide hormones |
HHEX, PRKDC, PRKACA |
| 2762 |
Negative regulation of myeloid leukocyte differentiation |
FSTL3, INHA |
| 32088 |
Negative regulation of NFκB activity |
POP1, SIVA |
| 51384 |
Response to glucocorticoids |
CEBPA, CAV1, PRKACA |
| 16481 |
Negative regulation of transcription |
CEBPA, HHEX, CAV1, HMGB2, FST, HELLS |
