Table 3.
Histocompatibility data.
| I. Original intended donor | |||||||
|---|---|---|---|---|---|---|---|
| Flow Cross match | DSA | ||||||
| Patient | Cum cPRA | pre- desensitization T cell XM auto/allo | pre- desensitization B cell XM auto/allo | post- desensitization T cell XM auto/allo | post- desensitization B cell XM auto/allo | pre- desensitization DSA (MFI) | post- desensitization DSA (MFI) |
| Case 1 | 100% | NA/475 | NA/477 | 112/250 | 134/320 | A2 (913–1780) A29 (613–758) B44 (8667–9262) |
A2 (571–922) A29 (501–561) B44 (6882–7972) |
| Case 2 | 100% | NA/8 | NA/288 | 50/63 | 27/338 | A24 (1154–1582) DQ2 (15799–19749) |
A24 (Neg) DQ2 (19304–21311) |
| Case 3 | 100% | 98/383 | 177/434 | NA | NA | A3 (13068) A68 (9535–9931) DR1 (5855–6021) DQ5 (8761–14004) DQ8 (849–1290) |
A3 (5696) A68 (5960–9204) DR1 (16942–17523) DQ5 (13911–15814) DQ8 (175–1319) |
| Case 4 | 100% | NA/399 | NA/361 | 30/327 | 24/325 | A68 (5445–6209) B44 (15137–15455) |
A68 (5220–5652) B44 (9750–9790) |
| Case 5 | 100% | 17/439 | 50/464 | NA | NA | A2 (528–1467) A26 (1165) B62 (2044) DR53 (7181–9685) DQ9 (669) |
A2 (1543–2209) A26 (757) B62 (556) DR53 (7493–9862) DQ9 (Neg) |
| II. KPD donor or Deceased donor | |||||||
|---|---|---|---|---|---|---|---|
| Flow Cross match | DSA | ||||||
| Patient | Cum cPRA | pre- desensitization T cell XM auto/allo | pre- desensitization B cell XM auto/allo | post- desensitization T cell XM auto/allo | post- desensitization B cell XM auto/allo | pre- desensitization DSA (MFI) | post- desensitization DSA (MFI) |
| Case 1 | 100% | NA | NA | 111/148 | 124/245 | A2 (913–1780) | A2 (571–922) |
| Case 2 | 100% | NA | NA | 48/39 | 47/228 | DR13 (591–1755) DQ6 (805) |
DR13 (Neg) DQ6 (Neg) |
| Case 3 | 100% | 243/325 | 257/324 | 130/171 | 148/254 | A29 (3314–3967) B45 (899) DR4 (441–965) DR53 (1435–2373) DQ2 (473–1935) |
A29 (1279–1498) B45 (Neg) DR4 (Neg) DR53 (552–706) DQ2 (Neg) |
| Case 4 | 100% | NA | NA | 46/0 | 30/14 | None | None |
| Case 5 | 100% | NA | NA | 0/40 | 1/2 | B62 (2044) | B62 (556) |