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Synergistic inhibition of cell growth. Cell proliferation was analyzed using the MTT assay. Cells were treated with fucoidan extract (FE), Cisplatin (CDDP), Tamoxifen (TAM) or Paclitaxel (TAXOL) alone or in combination for 48 h (n = 5). Results represent the mean ± SD from three independent experiments. A significant difference from control is indicated by p < 0.05 (#) or p < 0.01 (##); a significant difference from single treatments is indicated by p < 0.05 (*) or p < 0.01 (**).
