Skip to main content
. 2013 Jan 10;11(1):99–113. doi: 10.3390/md11010099

Figure 3.

Figure 3

Histomorphometric analysis of the effect of lemnalol on MSU-induced infiltration. (A) Representative photographs of the synovial tissue from control, MSU, MSU + colchicine and MSU + lemnalol groups after staining with hematoxylin and eosin. 24 h after the injection of MSU crystals, histologic analysis of infrapatellar synovium and subsynovial tissue demonstrated a marked increase in the number of neutrophils. Lemnalol and colchicine reduced the severity of the MSU crystal-induced neutrophil infiltration. There was a marked reduction in neutrophil influx in the lemnalol group; (B) WBC (white blood cell) count in the ankle-joint synovium (WBC cell per square millimeter) (C) Neutrophil count in the ankle-joint synovium (neutrophils per square millimeter). WBC and neutrophil counts were both elevated in the MSU-ankle group as compared to the control-ankle group. The MSU-ankle + colchicine group exhibited significantly reduced WBC and neutrophil counts compared with the MSU-ankle group. The MSU-ankle + lemnalol group exhibited significantly lower WBC and neutrophil counts compared with the MSU-ankle + colchicine group. Scale bars: 50 μm for all images (*p < 0.05 compared to the MSU group; #p < 0.05 compared to the MSU + colchicine group).