Table 1. Demographic, clinical, and laboratory characteristics of cirrhosis patients with an acute episode of HE at hospital admittance and 6 weeks after the HE episode (follow-up).
Study | Admittance | Follow-up |
---|---|---|
Number | 18 | 14 |
Age (years) | 60±10 | 59±11 |
Male/female | 13/5 | 10/4 |
Etiology | ||
Hepatitis C virus | 2 | 2 |
Alcohol | 8 | 5 |
Hepatitis C virus+alcohol | 3 | 3 |
Other | 5 | 4 |
HE gradea | ||
0 | 7 | 12 |
I | 5 | 2 |
II | 3 | 0 |
IV | 2 | 0 |
Child Pugh A/B/C | 1/4/2 | 0/5/6 |
Biochemical parametersb | ||
Prothrombin activity (%) | 53.2±13.9 | 64.0±17.2 |
Sodium (mEq/L) | 134.6±6.3 | 136.3±3.8 |
Potassium (mEq/L) | 4.0±0.6 | 4.4±0.3 |
Creatinine (mg/dL) | 1.1±0.7 | 0.9±0.3 |
Total bilirubin (mg/dL) | 2.8±1.0 | 2.2±1.1 |
Conjugated bilirubin (mg/dL) | 1.1±0.4 | 0.9±0.5 |
Albumin (g/dL) | 3.3±0.6 | 3.3±0.4 |
Aspartate transaminase (IU/L) | 58.6±48.8 | 68.5±59.3 |
Alanine transaminase (IU/L) | 36.9±32.3 | 47.7±40.2 |
Alkaline phosphatase (IU/L) | 118.8±47.0 | 144.9±74.1 |
Gamma-glutamyl transpeptidase (IU/L) | 96.0±79.1 | 110.2±35.8 |
Plasma ammonia concentration (μM) | 105.8±53.5 | 89.5±47.8 |
West Haven criteria.
Determined in venous blood samples.