Figure 3.

lag-2 expression in different mutants. Plot of lag-2 mRNA counts in Pn.p versus Pn.a in WT animals. (A) In animals with inhibition of Wnt/β-catenin asymmetry pathway, mom-4; lit-1 (B), multiple-ligand mutant, egl-20; cwn-1; cwn-2, (C) and double-receptor mutant, mom-5; lin-17 (D). Dotted lines divide the plot of lag-2 expression in Pn.p versus Pn.a into regions for correct polarity, loss of polarity and reverse polarity. Fractions of cells that fall into these three regions are indicated on the plots.