Table 3.
Hydrogen bond interactions of Drosophila melanogaster AnCE with Ang II, BK, Thr6–BK and BPPb peptides
| Ang II peptide | BPPb peptide | BK peptide | Thr6–BK peptide | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligand atom | Interacting atom from AnCE (and Zn ion) | Distance (Å) | Ligand atom | Interacting atom from AnCE (and Zn ion) | Distance (Å) | Ligand atom | Interacting atom from AnCE (and Zn ion) | Distance (Å) | Ligand atom | Interacting atom from AnCE (and Zn ion) | Distance (Å) |
| Y4 N | A340 O | 3.1 | K3 N | A340 O | 2.9 | ||||||
| Y4 O | A340 N | 2.8 | K3 O | A340 N | 2.9 | ||||||
| Y4 OH | T387 OG1 | 2.7 | |||||||||
| R1 O | H367 NE2 | 3.0 | R1 O | H367 NE2 | 3.1 | ||||||
| I5 O | Y507 OH | 2.7 | I4 O | Y507 OH | 2.6 | R1 O | Y507 OH | 2.6 | R1 O | Y507 OH | 2.6 |
| I5 O | Zinc ion | 2.2 | I4 O | Zinc ion | 2.4 | R1 O | Zinc ion | 2.5 | R1 O | Zinc ion | 2.5 |
| R1 N | H371 NE2 | 3.1 | R1 N | H371 NE2 | 3.2 | ||||||
| R1 NH1 | Y496 OH | 3.0 | R1 NH1 | Y496 OH | 3.0 | ||||||
| H6 N | A338 O | 3.2 | |||||||||
| H6 O | H337 NE2 | 2.6 | P5 O | H337 NE2 | 2.8 | P2 O | H337 NE2 | 2.7 | P2 O | H337 NE2 | 2.8 |
| H6 O | H497 NE2 | 2.9 | P5 O | H497 NE2 | 3.0 | P2 O | H497 NE2 | 3.1 | P2 O | H497 NE2 | 3.2 |
| P7 O | Y504 OH | 2.6 | P6 O | Y504 OH | 2.6 | P3 O | Y504 OH | 2.5 | P3 O | Y504 OH | 2.5 |
| P7 O | K495 NZ | 2.7 | P6 O | K495 NZ | 2.7 | P3 O | K495 NZ | 2.7 | P3 O | K495 NZ | 2.7 |
| P7 O | Q265 NE2 | 3.2 | P6 O | Q265 NE2 | 3.0 | ||||||