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. 2012 Sep 13;22(4):554–566. doi: 10.1089/scd.2011.0709

Table 3.

In Vivo Tumorigenicity and Treatment (Side Population and Nonside Population Cells of GBC-SD)

Group Volume D0 (mm3) Volume D2 (mm3) Volume D4 (mm3) Volume D6 (mm3) Volume D8 (mm3)
SP (GBC-SD)
 Con 0.101±0.011 0.139±0.013 0.199±0.022 0.277±0.021 0.379±0.025
 CDDP 0.101±0.012 0.123±0.012 0.174±0.021 0.212±0.02 0.301±0.049
 Emodin 0.102±0.074 0.108±0.098 0.142±0.015a 0.183±0.029a 0.258±0.036a
 CDDP+emodin 0.103±0.01 0.092±0.011a 0.084±0.01a 0.078±0.011a 0.074±0.009a
Non-SP (GBC-SD)
 Con 0.102±0.008 0.121±0.017 0.17±0.025 0.232±0.037 0.312±0.04
 CDDP 0.102±0.008 0.103±0.008a 0.136±0.028a 0.181±0.022a 0.25±0.028a
 Emodin 0.102±0.01 0.12±0.019 0.169±0.014 0.221±0.017 0.309±0.027
 CDDP+emodin 0.1±0.007 0.093±0.002a 0.084±0.005a 0.074±0.005a 0.07±0.005a
a

P<0.05, experimental group compared with the control group.

Emodin sensitizes SP and non-SP cells of GBC-SD to CDDP cytotoxicity in xenograft tumors. D, day; (n=6).