Table 1. Synopsis of human platelet alloantigens (HPAs) located on β3 integrin.
HPA | Synonym | Nucleotide | Amino acid | Domain | Reference |
---|---|---|---|---|---|
1a 1b |
Zwa, PlA1 Zwb, PlA2 |
T176 C176 |
Leu33 Pro33 |
PSI | 17 |
4a 4b |
Yukb, Pena Yuka, Penb |
G506 A506 |
Arg143 Gln143 |
βA | 17 |
6bW | Caa, Tua | 1544G>A | Arg489Gln | EGF1–2 | 17 |
7bW | Moa | 1297C>G | Pro407Ala | Hybrid | 17 |
8bW | Sra | 1984C>T | Arg636Cys | β–TD | 17 |
10bW | Laa | 263G>A | Arg62Gln | Hybrid | 17 |
11bW | Groa | 1976G>A | Arg633His | β–TD | 17 |
14bW | Oea | 1909–1911 del AAG | Lys611del | β–TD | 17 |
16bW | Duva | 497C>T | Thr140Ile | βA | 17 |
17bW | Vaa | 662C>T | Thr195Met | βA | 18 |
19bW | Staa | 487A>C | Lys137Gln | βA | 8 |
21bW | Nosa | 1960G>A | Glu628Lys | β−TD | 8 |
n.a. | Hita | 1297C>T | Pro407Ser | Hybrid | 19 |
n.a. | Mata | 520A>G | Gln141Arg | βA | 20 |
n.a. | Seca | 1818G>T | Lys580Asn | EGF4 | this study |