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REM and NREM sleep over 48 h (24 h before and after treatment with saline (SAL) or clomipramine (CLI) in rats). (A) REM sleep after treatment was significantly reduced in the CLI group compared with both the SAL group (P < 0.001) and the baseline (P < 0.001). (B) No significant differences were seen in NREM sleep either between groups or between treatments.
